Vaccine approval will be based on recommendations made by the National Technical Advisory Group on Immunization (NTAGI) Covid-19 task force last week.
Should the vaccine gain approval, it would be the first time that a booster dose of a Covid vaccine different from that used for the primary vaccination has been authorized in the country.
“Corbevax will be considered a precautionary dose after the completion of 6 months or 26 weeks from the date of administration of the second dose of the Covaxin or Covishield vaccines for persons over the age of 18 allowing the use of Corbevax as a heterologous Covid-19 vaccine for administration of a precautionary dose in this age group,” PTI said citing a source.
This will be in addition to existing guidelines for the administration of homologous precautionary doses of Covaxin and Covishield vaccines.
India’s first locally developed RBD protein subunit vaccine, Corbevax, is currently being used to inoculate children aged 12 to 14 as part of the Covid-19 vaccination programme.
The Covid-19 Working Group (CWG), at its July 20 meeting, reviewed data from the randomized, double-blind Phase 3 clinical study that evaluated the immunogenicity and safety of the booster dose Corbevax vaccine when given to a Covid-19 negative adult. volunteers aged 18 to 80 previously vaccinated with two doses of Covishield or Covaxin.
“Following review of the data, the CWG observed that the Corbevax vaccine can induce a significant increase in antibody titers when given to those who received either Covaxin or Covishield, which is likely to be protective. according to neutralization data as well,” the PTI source said.
The Drug Controller General of India (DCGI) on June 4 approved Corbevax as a precautionary dose for people aged 18 and above.
India started administering precautionary doses of vaccines to healthcare and frontline workers and people aged 60 and above with co-morbidities from January 10.
The country started vaccinating children aged 12 to 14 from March 16 and also removed the comorbidity clause making all people over the age of 60 eligible for the precautionary dose of the Covid vaccine.
India on April 10 began administering precautionary doses of Covid-19 vaccines to all people over the age of 18.
(With PTI entries)